IMMATURE PLATELET FRACTION EXAMINATION IN IMMUNE THROMBOCYTOPENIC PURPURA

  • Atika Indah Sari Fakultas Kedokteran, Universitas Andalas
Keywords: thrombocytopenia, bleeding, purpura, immune, platelet

Abstract

Introduction: Immune Thrombocytopenic Purpura is an abnormality of decreased platelets caused by the destruction of platelets which is mediated by the immune and usually occurs in young adult women. The clinical manifestations are mild bleeding in the skin, such as petechiae, ecchymosis, and intracranial hemorrhage. IPF could help clinicians in diagnosing ITP. Case report: It had been reported a 22-year-old female patient who has diagnosed with thrombocytopenia et causa Immune Thrombocytopenia Purpura and moderate anemia et causa acute bleeding and treated with corticosteroid. Conclusion: IPF could help in diagnosing ITP.

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Author Biography

Atika Indah Sari, Fakultas Kedokteran, Universitas Andalas

 

 

References

Provan D, Arnold DM, Bussel JB, Chong BH, Cooper N, Gernsheimer T, Ghanima W, et al. Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood advances. 2019 Nov 26;3(22):3780-817.
Neunert C, Terrell DR, Arnold DM, Buchanan G, Cines DB, Cooper N, Cuker A, et al. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood advances. 2019 Dec 10;3(23):3829-66.
Poston J, Gernsheimer T. Management of immune thrombocytopenia in pregnancy. Annals of Blood. 2021 Mar 6;6(0):1-8.
Michel M. Immune thrombocytopenic purpura: epidemiology and implications for patients. Eur J Haematol. 2009;82(s71):3–7.
McCrae K. Immune thrombocytopenia: No longer ‘idiopathic’. CCJM. 2011. 78(6):358-73
Saidah F, Sjakti HA. Laporan kasus berbasis bukti Peran Pemeriksaan Immature Platelet Fraction dalam Imun Trombositopenia Evaluation of Immature Platelet Fraction in The Diagnosis of Immune Thrombocytopenia: Evidence Based Case Report. Sari Pediatri. 2018;20(3):190–6.
Naz A, Mukry SN, Shaikh MR, Bukhari AR, Shamsi TS. Importance of immature platelet fraction as predictor of immune thrombocytopenic purpura. Pak J Med Sci. 2016;32(3):575–9.
Saeidi S, Jaseb K, Asnafi AA, Rahim F, Pourmotahari F, Mardaniyan S, Yousefi H, Alghasi A, Shahjahani M, Saki N. Immune thrombocytopenic purpura in children and adults: a comparative retrospective study in IRAN. International journal of hematology-oncology and stem cell research. 2014 Jul 1;8(3):30.
Ayesh MH, Alawneh K, Khassawneh B, Khader Y, Kasasbeh A. Adult primary and secondary immune thrombocytopenic purpura: a comparative analysis of characteristics and clinical course. Clinical and Applied Thrombosis/Hemostasis. 2013 Jun;19(3):327-30.
Moulis G, Palmaro A, Montastruc JL, Godeau B, Lapeyre-Mestre M, Sailler L. Epidemiology of incident immune thrombocytopenia: a nationwide population-based study in France. Blood, The Journal of the American Society of Hematology. 2014 Nov 20;124(22):3308-15.
Chapin J, Lee CS, Zhang H, Zehnder JL, Bussel JB. Gender and duration of disease differentiate responses to rituximab–dexamethasone therapy in adults with immune thrombocytopenia. American journal of hematology. 2016 Sep;91(9):907-11.
Arnold DM. Bleeding complications in immune thrombocytopenia. Hematology Am Soc Hematol Educ Program. 2015;237–42
Ho-Tin-Noé B, Jadoui S. Spontaneous bleeding in thrombocytopenia: Is it really spontaneous? Vol. 25, Transfusion Clinique et Biologique. Elsevier Masson SAS; 2018. p. 210–6.
Konkle B. Disorders of Platelets and Vessel Wall. In : Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscaizo J. Harisson’s Principles of Internal Medicine. 18th Edition. New York, McGraw-Hill. 2012
McMillan R. Hemorrhagic Disorders: Abnormalities of Platelet and Vascular Function. In: Goldman Ausiello. Cecil Medicine. 23rd Edition. Philadelphia. Saunders, Elsevier. 2008
Stasi R. How to approach thrombocytopenia. The American Society of Hematology Evidence-based approaches to cytopenias. Hematology 2012;2012(1):191-97.
Bozkurt Turhan A, Canan Özdemir Z, Bör Ö. Use of Single- or Two-dose Pulse Methylprednisolone in the Treatment of Acute Immune Thrombocytopenic Purpura. The Medical Bulletin of Sisli Hospital. 2018 Dec 18;52(4):279–84
Published
2023-05-27
How to Cite
Indah Sari, A. (2023). IMMATURE PLATELET FRACTION EXAMINATION IN IMMUNE THROMBOCYTOPENIC PURPURA. Jurnal Scientia, 12(02), 1820-1823. https://doi.org/10.58471/scientia.v12i02.1460